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7th Dutch Breast Pathology Course

November 7-8, 2018

Preventing overtreatment of breast cancer precursors

Since the introduction of screening strategies, the incidence of Ductal Carcinoma In Situ (DCIS) has increased manifold, without a decrease in the incidence of advanced stages of breast cancer. This suggests that many DCIS lesions are detected that would have never caused any clinical symptoms if screening would have been omitted. This so-called overdiagnosis results in overtreatment, as we cannot distinguish yet which DCIS lesions are harmless and which ones potentially hazardous. As a consequence, many women with DCIS lesions carry the burden of ineffective, needless treatment.

To conquer this, pathologists should try to find and validate features that improve our risk stratification for each individual woman with DCIS.

This international 'Dutch Breast Pathology Course' aims to explore our possibilities, challenges, and limitations in diagnosing and classifying breast cancer precursor lesions in the clinical context. Therefore, input will and has to be provided by different disciplines as well, i.e. epidemiology, radiology, surgery, radiotherapy and the patient perspective.

To achieve all this, we intend to encourage you to practice, interact, discuss, and come up with your ideas how to solve this breast cancer precursor dilemma. We look very much forward to embark with you on this challenging mission.

  • Inspiring and clinically relevant lectures
  • Informative case studies
  • Challenging debates
  • Lots of interaction and networking

General information


November 7-8, 2018


The Netherlands Cancer Institute - Antoni van Leeuwenhoek
Conference Room Z4
Plesmanlaan 121
1066 CX Amsterdam, The Netherlands

More information

Sabine de Groot
020 512 7872


Programme at a glance

Detection, diagnostics and treatment of breast precursor lesions will be discussed in depth in relation to the prevention of overtreatment, including the relevance of precursor lesions in the low-grade spectrum, patient perspectives on treatment decisions and current trials on DCIS. The issue of interobserver variability will be highlighted and interactively discussed for improvement of our current classification system.

Before the course we would like each participating pathologist to review 150 DCIS cases using digitized whole slides (8 hours) with an easy to use digital scoring system. For both the pathological review and the course accreditation is requested separately. In addition all pathologists finishing reviewing these cases will become co-author of the final analysis.

The complete programme can be found here.